Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G006950Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (574 aa)    
Predicted Functional Partners:
DGUA_6G006926
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.984
DGUA_6G007178
Blast:Ornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.956
DGUA_6G007032
Dihydrolipoyl dehydrogenase.
  
 0.953
DGUA_6G017504
Blast:Glutamate dehydrogenase, mitochondrial; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.950
DGUA_6G005554
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
   
 
 0.946
DGUA_6G017260
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
   
 
 0.946
DGUA_6G017499
Blast:Bifunctional glutamate/proline--tRNA ligase.
  
 
 0.946
DGUA_6G012156
Aspartate aminotransferase.
   
 0.945
DGUA_6G004995
Blast:Glutamate dehydrogenase, mitochondrial; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.944
DGUA_6G011992
Glutamine synthetase.
  
 
 0.941
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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