Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G002290Blast:Far upstream element-binding protein 3. (832 aa)    
Predicted Functional Partners:
DGUA_6G014701
Blast:Poly(U)-binding-splicing factor half pint.
   
 
 0.954
DGUA_6G005147
Blast:Protein held out wings.
   
 
 0.914
DGUA_6G017341
Blast:Polypyrimidine tract-binding protein 1.
   
 
 0.716
MED17
Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
   0.711
DGUA_6G002092
Blast:14-3-3 protein zeta; Belongs to the 14-3-3 family.
    
  0.705
DGUA_6G011247
Blast:E3 ubiquitin-protein ligase HUWE1.
   
 
 0.697
DGUA_6G016123
Non-specific serine/threonine protein kinase.
   
 0.694
DGUA_6G017165
Blast:Myelin expression factor 2.
   
 
 0.683
DGUA_6G006944
Blast:Poly(RC)-binding protein 3.
   
 
 0.682
DGUA_6G009442
Blast:Survival motor neuron protein.
    
 
 0.670
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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