Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G007261Blast:DNA excision repair protein haywire. (801 aa)    
Predicted Functional Partners:
DGUA_6G020285
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
  
 0.999
DGUA_6G002037
Blast:TFIIH basal transcription factor complex helicase XPD subunit.
   
 0.998
DGUA_6G009792
General transcription factor IIH subunit.
    
 0.998
DGUA_6G002421
Blast:General transcription factor IIH subunit 1.
   
 0.997
DGUA_6G001743
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
    
 0.995
DGUA_6G010813
Blast:DNA repair protein complementing XP-A cells homolog.
    
 0.994
DGUA_6G006649
Blast:Cyclin-H; Belongs to the cyclin family.
    
 0.993
DGUA_6G003797
Blast:DNA repair protein complementing XP-C cells homolog.
   
 0.991
DGUA_6G019404
Blast:DNA repair endonuclease XPF.
  
 0.990
DGUA_6G013398
Blast:Transcription initiation factor IIB.
    
 0.990
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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