Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
DGUA_6G002488Blast:EH domain-binding protein 1. (355 aa)    
Predicted Functional Partners:
DGUA_6G018081
Blast:Type I inositol 1,4,5-trisphosphate 5-phosphatase.
     
 0.932
DGUA_6G019685
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
 0.849
DGUA_6G020082
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.844
DGUA_6G014587
Blast:Phosphatidylinositide phosphatase SAC1.
 
  
 0.838
DGUA_6G002501
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
      
 0.831
DGUA_6G004157
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.830
DGUA_6G012631
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.825
DGUA_6G009438
Blast:Multiple inositol polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family.
     
 0.819
DGUA_6G015930
Blast:Inositol polyphosphate 1-phosphatase.
     
 0.819
DGUA_6G011349
Uncharacterized protein.
     
 0.816
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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