Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G002416Uncharacterized protein. (280 aa)    
Predicted Functional Partners:
DGUA_6G006210
Blast:Outer dense fiber protein 3-B.
      
 0.675
DGUA_6G020936
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.
      
 0.665
DGUA_6G007932
Blast:Probable prefoldin subunit 6.
    
 
 0.552
DGUA_6G000936
Blast:ATP synthase subunit d, mitochondrial.
      
 0.544
DGUA_6G016337
Blast:14-3-3 protein epsilon; Belongs to the 14-3-3 family.
    
   0.478
DGUA_6G007531
Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.
      
 0.440
DGUA_6G004745
Blast:Prefoldin subunit 1.
      
 0.438
DGUA_6G015944
Blast:Probable prefoldin subunit 5.
      
 0.436
DGUA_6G016314
Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.
      
 0.432
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (22%) [HD]