Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
DGUA_6G007686MADF domain-containing protein. (584 aa)    
Predicted Functional Partners:
DGUA_6G000882
Blast:H/ACA ribonucleoprotein complex subunit 4.
   
 
 0.783
DGUA_6G006503
Blast:H/ACA ribonucleoprotein complex subunit 2-like protein.
   
 
 0.777
DGUA_6G001751
Blast:H/ACA ribonucleoprotein complex subunit 3.
   
 
 0.765
DGUA_6G016670
Blast:Protein SHQ1 homolog.
   
 
 0.644
DGUA_6G019552
Uncharacterized protein.
      
 0.551
DGUA_6G018293
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...]
    
 
 0.492
DGUA_6G001763
Blast:Protein LTV1 homolog.
   
    0.484
DGUA_6G000766
Blast:Probable tRNA pseudouridine synthase 2.
   
 
 0.452
DGUA_6G018690
Blast:WD repeat-containing protein 46.
   
    0.423
DGUA_6G018071
Blast:U3 small nucleolar ribonucleoprotein protein IMP4.
   
    0.410
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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