Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
DGUA_6G002622Blast:Cap-specific mRNA (Nucleoside-2'-O-)-methyltransferase 2. (697 aa)    
Predicted Functional Partners:
snRNP-U1-C
U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.
    
   0.896
DGUA_6G018860
PID domain-containing protein.
    
   0.879
DGUA_6G020790
mRNA cap guanine-N7 methyltransferase.
      
 0.830
DGUA_6G003042
Blast:Protein FAM192A.
      
 0.771
DGUA_6G009263
Blast:Ribonuclease Oy; Belongs to the RNase T2 family.
      
 0.682
DGUA_6G018948
Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.
   
  
 0.674
DGUA_6G005865
Blast:Cardio acceleratory peptide 2b.
      
 0.666
DGUA_6G017237
Uncharacterized protein.
      
 0.665
DGUA_6G013428
Blast:Conserved oligomeric Golgi complex subunit 4.
      
 0.645
DGUA_6G005100
Small nuclear ribonucleoprotein G.
    
   0.636
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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