Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G003506Blast:F-box/SPRY domain-containing protein 1. (255 aa)    
Predicted Functional Partners:
DGUA_6G010249
Blast:E3 ubiquitin-protein ligase highwire.
    
 
 0.987
DGUA_6G001894
Blast:S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.958
DGUA_6G003389
Blast:Cullin homolog 1; Belongs to the cullin family.
    
 0.921
DGUA_6G006658
Blast:Cullin homolog 1; Belongs to the cullin family.
    
 0.921
DGUA_6G013564
Blast:Cullin-3-A; Belongs to the cullin family.
    
 0.834
DGUA_6G015870
Blast:Cullin-5; Belongs to the cullin family.
    
 0.816
DGUA_6G006420
Blast:F-box only protein 9.
     
 0.783
DGUA_6G007118
Blast:Alpha-aminoadipic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
 0.766
DGUA_6G001061
Blast:mRNA export factor.
    
 
 0.763
DGUA_6G005428
Blast:Aldehyde dehydrogenase X, mitochondrial; Belongs to the aldehyde dehydrogenase family.
     
  0.752
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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