Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G003518Blast:Enkurin domain-containing protein 1. (462 aa)    
Predicted Functional Partners:
DGUA_6G016315
Blast:ATP-dependent DNA helicase 2 subunit 1.
    
 0.708
DGUA_6G011057
Blast:Protein DENND6B.
    
 0.702
DGUA_6G008720
Blast:DNA ligase 4; Belongs to the ATP-dependent DNA ligase family.
  
 0.693
DGUA_6G017387
Blast:Uncharacterized protein F21D5.5.
    
 0.673
DGUA_6G005369
DNA ligase.
  
 0.645
DGUA_6G000597
DNA ligase.
  
 0.613
DGUA_6G010468
Uncharacterized protein.
  
 0.613
DGUA_6G016943
Blast:DNA cross-link repair protein SNM1.
  
 
 0.578
DGUA_6G019846
Poly [ADP-ribose] polymerase.
    
 0.576
Fen1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.565
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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