Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G003818Endonuclease. (309 aa)    
Predicted Functional Partners:
DGUA_6G020199
Ku_PK_bind domain-containing protein.
    
 
 0.976
DGUA_6G009455
Blast:Prostaglandin E synthase 2.
   
   0.960
DGUA_6G000739
Blast:Apoptosis 2 inhibitor.
    
 
 0.958
DGUA_6G004151
Blast:Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog.
    
 
 0.943
DGUA_6G005144
Blast:Serine protease HTRA2, mitochondrial.
   
  
 0.835
DGUA_6G014131
Blast:Cytochrome c-1; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
  
 0.815
DGUA_6G014130
Blast:Cytochrome c-2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
  
 0.815
DGUA_6G012128
Blast:Putative apoptosis-inducing factor 1, mitochondrial.
    
 
 0.774
DGUA_6G001672
Blast:Ribonuclease Z, mitochondrial.
   
 
 0.674
DGUA_6G002483
Blast:Apoptotic protease-activating factor 1.
      
 0.666
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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