Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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[Homology]
Score
DGUA_6G010450Blast:Cofilin/actin-depolymerizing factor homolog; Belongs to the actin-binding proteins ADF family. (156 aa)    
Predicted Functional Partners:
DGUA_6G011624
Blast:LIM domain kinase 1.
   
 0.990
DGUA_6G005216
Blast:Nicotinamide mononucleotide adenylyltransferase 1.
    
 0.942
DGUA_6G004703
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
   
 0.934
DGUA_6G006885
Blast:Actin-interacting protein 1.
   
 
 0.914
DGUA_6G012842
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.896
DGUA_6G014140
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.867
DGUA_6G008962
Blast:Cdc42 homolog.
   
 0.861
DGUA_6G006741
Blast:FH2 domain-containing protein 1.
    
 
 0.849
DGUA_6G005702
Blast:Wiskott-Aldrich syndrome protein homolog.
    
 
 0.834
DGUA_6G019788
Blast:Gelsolin.
   
  
 0.831
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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