Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G011099Blast:cAMP-specific 3',5'-cyclic phosphodiesterase, isoforms N/G. (373 aa)    
Predicted Functional Partners:
Adk2
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
     
 0.889
DGUA_6G012772
Phosphodiesterase.
    
 0.866
DGUA_6G000530
Blast:Adenosine kinase.
     
 0.859
DGUA_6G000391
Blast:High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; Belongs to the cyclic nucleotide phosphodiesterase family.
    
 0.856
DGUA_6G004867
Blast:Protein phosphatase PHLPP-like protein.
    
 0.852
DGUA_6G017719
Blast:Peripheral plasma membrane protein CASK; Belongs to the MAGUK family.
    
 0.846
DGUA_6G001722
Blast:Trifunctional nucleotide phosphoesterase protein YfkN.
     
 0.842
DGUA_6G003134
Blast:Protein 5NUC; Belongs to the 5'-nucleotidase family.
     
 0.842
DGUA_6G014733
Blast:Adenine phosphoribosyltransferase.
     
 0.841
DGUA_6G018009
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.837
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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