Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G006931Uncharacterized protein. (1534 aa)    
Predicted Functional Partners:
DGUA_6G017908
Hermansky-Pudlak syndrome 5 protein homolog; Has a role in the biogenesis of eye pigment granules. Eye pigment granules are specialized forms of late endosomes or lysosomes. Biogenesis of pigment granules in the eye requires molecular components required for protein delivery to lysosomes.
   
 
 0.951
DGUA_6G000720
Blast:Hermansky-Pudlak syndrome 4 protein.
      
 0.824
DGUA_6G017517
Blast:Biogenesis of lysosome-related organelles complex 1 subunit 5.
      
 0.785
DGUA_6G007357
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis.
      
 0.745
DGUA_6G006682
Blast:Dysbindin protein homolog.
      
 0.726
DGUA_6G003607
Blast:Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family.
      
 0.663
DGUA_6G010677
AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family.
      
 0.659
DGUA_6G003514
Blast:WD repeat-containing protein CG11141.
   
 
 0.648
DGUA_6G014806
Blast:Centrosomal protein of 290 kDa.
      
 0.635
DGUA_6G002002
Blast:Hermansky-Pudlak syndrome 1 protein.
      
 0.597
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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