Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G006796Blast:Ras-GEF domain-containing family member 1B. (676 aa)    
Predicted Functional Partners:
DGUA_6G014432
Blast:Protein son of sevenless.
   
 0.762
DGUA_6G001289
Blast:Protein E(Sev)2B.
     
 0.756
DGUA_6G017167
Uncharacterized protein.
    
  0.756
DGUA_6G007994
Blast:SHC-transforming protein 1.
     
  0.752
DGUA_6G008594
Blast:Ras GTPase-activating protein 1.
    
 
 0.486
DGUA_6G002835
Blast:Netrin receptor unc-5.
      
 0.440
DGUA_6G004808
Blast:Cyclin-K; Belongs to the cyclin family.
     
  0.431
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (52%) [HD]