Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G011369Blast:Cathepsin E-B; Belongs to the peptidase A1 family. (417 aa)    
Predicted Functional Partners:
DGUA_6G018216
Uncharacterized protein; Belongs to the calycin superfamily. Lipocalin family.
   
    0.687
DGUA_6G020116
Blast:Cathepsin B; Belongs to the peptidase C1 family.
   
 0.660
DGUA_6G015809
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
  
 0.607
DGUA_6G005039
Blast:Renin receptor.
   
 0.575
DGUA_6G017236
Blast:Putative cysteine proteinase CG12163.
   
 0.468
DGUA_6G017235
Blast:Putative cysteine proteinase CG12163; Belongs to the peptidase C1 family.
   
 0.468
DGUA_6G003129
Blast:Cathepsin L; Belongs to the peptidase C1 family.
   
 0.430
DGUA_6G005811
Blast:Prosaposin.
   
 0.413
DGUA_6G001765
Blast:Cathepsin L; Belongs to the peptidase C1 family.
   
 0.411
DGUA_6G009787
Blast:Cathepsin L; Belongs to the peptidase C1 family.
   
 0.411
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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