Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G011154Blast:Neurogenic locus Notch protein. (445 aa)    
Predicted Functional Partners:
DGUA_6G017633
DUF725 domain-containing protein.
      
 0.789
DGUA_6G020783
Blast:Suppressor of hairless protein.
    
 0.595
DGUA_6G018709
Integrin beta; Belongs to the integrin beta chain family.
    
 0.556
DGUA_6G015585
Blast:Glutamate receptor ionotropic, kainate 2.
   
 0.547
DGUA_6G002093
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
    
 
 0.539
DGUA_6G002692
Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.
    
 0.523
DGUA_6G017666
Blast:Disintegrin and metalloproteinase domain-containing protein 10.
  
 
 0.515
DGUA_6G007782
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.500
DGUA_6G004458
Blast:Protein numb.
    
 0.472
DGUA_6G011742
Uncharacterized protein.
    
 0.446
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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