Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G011202Blast:Dynein heavy chain 6, axonemal. (4029 aa)    
Predicted Functional Partners:
DGUA_6G015838
Blast:Dynein light chain Tctex-type.
    
 0.850
DGUA_6G016096
Blast:Putative inner dynein arm light chain, axonemal.
  
 0.805
DGUA_6G008796
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 0.797
DGUA_6G016758
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 0.797
DGUA_6G002967
Blast:Probable dynactin subunit 2.
    
 0.762
DGUA_6G005251
Blast:Growth arrest-specific protein 8 homolog.
  
 
 0.698
DGUA_6G002291
Blast:Dynein intermediate chain 2, ciliary.
  
 0.684
Lis-1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.
   
 0.682
DGUA_6G015585
Blast:Glutamate receptor ionotropic, kainate 2.
    
 0.667
DGUA_6G005465
Blast:Coiled-coil domain-containing protein 147.
   
 0.648
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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