Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G012159Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (246 aa)    
Predicted Functional Partners:
DGUA_6G018517
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
   
 0.989
DGUA_6G017569
Blast:E3 ubiquitin-protein ligase HRD1.
    
 0.951
DGUA_6G017815
Blast:Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1.
   
 0.945
DGUA_6G013058
Blast:Endoplasmic reticulum lectin 1.
   
 0.942
DGUA_6G013891
Protein YIPF.
   
 0.881
DGUA_6G008158
Blast:Ubiquitin fusion degradation protein 1 homolog.
   
 
 0.877
DGUA_6G016054
Uncharacterized protein.
   
 0.877
DGUA_6G018457
Blast:Transmembrane protein 129.
    
 0.854
DGUA_6G001145
Blast:Transitional endoplasmic reticulum ATPase TER94; Belongs to the AAA ATPase family.
   
 0.828
DGUA_6G009563
Blast:Spermatogenesis-associated protein 5-like protein 1.
   
 0.828
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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