STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G012256Blast:Glutathione S-transferase C-terminal domain-containing protein homolog. (585 aa)    
Predicted Functional Partners:
DGUA_6G003412
Blast:28S ribosomal protein S28, mitochondrial.
   
  
 0.569
DGUA_6G015263
Blast:TRM112-like protein.
   
 0.543
DGUA_6G005229
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.513
DGUA_6G019011
Blast:NADH dehydrogenase (Ubiquinone) complex I, assembly factor 6 homolog.
    
 0.501
DGUA_6G000099
Blast:Selenocysteine-specific elongation factor.
   
 0.485
DGUA_6G020390
Blast:Bystin.
   
 0.473
DGUA_6G015236
Blast:Pre-rRNA-processing protein TSR1 homolog.
   
  0.472
DGUA_6G001962
40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.
    
  0.443
DGUA_6G005930
40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.
    
  0.437
DGUA_6G020382
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
    
  0.437
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.