Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G007774Blast:Nuclear hormone receptor HR78. (599 aa)    
Predicted Functional Partners:
DGUA_6G019600
Blast:Nuclear receptor corepressor 1.
   
 0.742
DGUA_6G006614
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.698
DGUA_6G005748
Blast:Juxtaposed with another zinc finger protein 1.
    
 
 0.680
DGUA_6G008589
Blast:Probable arginine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 
 0.574
DGUA_6G012506
Blast:Probable nuclear hormone receptor HR38.
    
 0.569
DGUA_6G014526
Blast:Possible lysine-specific histone demethylase 1.
    
 0.567
DGUA_6G012047
Blast:SUMO-conjugating enzyme UBC9-B; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.559
DGUA_6G008743
Blast:SUMO-conjugating enzyme UBC9-A.
    
 0.559
DGUA_6G015086
Blast:Four and a half LIM domains protein 2.
    
 0.559
DGUA_6G012616
Blast:SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.559
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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