MCM7 protein (Drosophila guanche) - STRING interaction network

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MCM7

DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (720 aa)

Predicted Functional Partners:

DGUA_6G003561

0.999

DGUA_6G003679

0.999

DGUA_6G011059

0.999

DGUA_6G011527

0.999

DGUA_6G018036

0.999

DGUA_6G017555

0.999

DGUA_6G008069

0.998

DGUA_6G003571

0.997

DGUA_6G013979

0.997

DGUA_6G019341

0.996

Your Current Organism:

Drosophila guanche

NCBI taxonomy Id: 7266
Other names: D. guanche

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGUA_6G003561	DGUA_6G003571	A0A3B0J6N2	A0A3B0J6N9	DNA helicase; Belongs to the MCM family.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.997
DGUA_6G003561	DGUA_6G003679	A0A3B0J6N2	A0A3B0J6V2	DNA helicase; Belongs to the MCM family.	Blast:DNA replication factor Cdt1.	0.998
DGUA_6G003561	DGUA_6G008069	A0A3B0J6N2	A0A3B0J6P1	DNA helicase; Belongs to the MCM family.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.997
DGUA_6G003561	DGUA_6G011059	A0A3B0J6N2	A0A3B0J7Z5	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
DGUA_6G003561	DGUA_6G011527	A0A3B0J6N2	A0A3B0JF20	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
DGUA_6G003561	DGUA_6G013979	A0A3B0J6N2	A0A3B0JMS4	DNA helicase; Belongs to the MCM family.	Blast:Protein MCM10 homolog.	0.995
DGUA_6G003561	DGUA_6G017555	A0A3B0J6N2	A0A3B0JQZ9	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
DGUA_6G003561	DGUA_6G018036	A0A3B0J6N2	A0A3B0JQH7	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
DGUA_6G003561	DGUA_6G019341	A0A3B0J6N2	A0A3B0KR52	DNA helicase; Belongs to the MCM family.	Blast:Cell division control protein 45 homolog.	0.998
DGUA_6G003561	MCM7	A0A3B0J6N2	A0A3B0JBE8	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
DGUA_6G003571	DGUA_6G003561	A0A3B0J6N9	A0A3B0J6N2	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.997
DGUA_6G003571	DGUA_6G003679	A0A3B0J6N9	A0A3B0J6V2	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Blast:DNA replication factor Cdt1.	0.999
DGUA_6G003571	DGUA_6G008069	A0A3B0J6N9	A0A3B0J6P1	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.999
DGUA_6G003571	DGUA_6G011059	A0A3B0J6N9	A0A3B0J7Z5	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.998
DGUA_6G003571	DGUA_6G011527	A0A3B0J6N9	A0A3B0JF20	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.997
DGUA_6G003571	DGUA_6G013979	A0A3B0J6N9	A0A3B0JMS4	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Blast:Protein MCM10 homolog.	0.965
DGUA_6G003571	DGUA_6G017555	A0A3B0J6N9	A0A3B0JQZ9	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.999
DGUA_6G003571	DGUA_6G018036	A0A3B0J6N9	A0A3B0JQH7	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.998
DGUA_6G003571	DGUA_6G019341	A0A3B0J6N9	A0A3B0KR52	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Blast:Cell division control protein 45 homolog.	0.992
DGUA_6G003571	MCM7	A0A3B0J6N9	A0A3B0JBE8	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.997

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