Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G000123Blast:Shugoshin. (442 aa)    
Predicted Functional Partners:
DGUA_6G011962
Serine/threonine-protein phosphatase.
    
   0.912
DGUA_6G007570
Blast:Separin.
      
 0.869
DGUA_6G013464
Blast:Aurora kinase B; Belongs to the protein kinase superfamily.
   
  
 0.832
DGUA_6G012395
Blast:Mitotic checkpoint serine/threonine-protein kinase BUB1.
      
 0.831
DGUA_6G001040
Blast:Protein ORD.
      
 0.831
DGUA_6G003709
Blast:Mitotic checkpoint serine/threonine-protein kinase BUB1.
      
 0.831
DGUA_6G000537
Blast:Inner centromere protein.
    
 
 0.788
DGUA_6G011502
Blast:Protein wings apart-like.
      
 0.787
DGUA_6G004429
Blast:Borealin.
   
  
 0.781
DGUA_6G005549
Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.
    
 
 0.747
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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