Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G010754Blast:Homeotic protein female sterile. (371 aa)    
Predicted Functional Partners:
DGUA_6G001048
Blast:Homeotic protein female sterile.
  
 
 
 0.669
DGUA_6G005229
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.607
DGUA_6G016565
Blast:Transcription initiation factor TFIID subunit 7.
    
 
 0.524
DGUA_6G006087
Histone H2A; Belongs to the histone H2A family.
    
 0.521
DGUA_6G013197
Blast:YEATS domain-containing protein 4.
    
 
 0.501
DGUA_6G001371
Blast:DNA methyltransferase 1-associated protein 1.
    
 
 0.493
DGUA_6G016748
Blast:Transcription initiation factor TFIID subunit 1.
    
 
 0.488
DGUA_6G001959
Blast:Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily.
    
 
 0.480
DGUA_6G015230
Blast:Transcription initiation factor TFIID subunit 8.
    
 
 0.479
DGUA_6G003936
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
    
 
 0.476
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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