Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G010195Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (602 aa)    
Predicted Functional Partners:
DGUA_6G018300
Blast:Actin-related protein 5; Belongs to the actin family.
   
 0.997
DGUA_6G008711
Blast:INO80 complex subunit C.
    
 0.996
DGUA_6G015449
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
    
 0.996
DGUA_6G007978
Uncharacterized protein.
    
 0.996
DGUA_6G002352
Blast:Actin-like protein 6B; Belongs to the actin family.
    
 0.995
DGUA_6G016503
Blast:Nuclear factor related to kappa-B-binding protein.
    
 0.993
DGUA_6G003898
Blast:INO80 complex subunit B.
    
 0.985
DGUA_6G005232
Blast:INO80 complex subunit D.
    
 0.985
DGUA_6G002042
Blast:Helicase domino.
   
 0.982
DGUA_6G007114
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
   
 0.969
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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