Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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co-expression
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[Homology]
Score
DGUA_6G010825Blast:Vacuolar protein sorting-associated protein 37C. (199 aa)    
Predicted Functional Partners:
DGUA_6G002909
Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
   
 0.998
DGUA_6G009927
Blast:Tumor susceptibility gene 101 protein.
   
 0.998
DGUA_6G017229
Blast:Vacuolar protein sorting-associated protein 37B.
     
 0.992
DGUA_6G011188
Blast:Multivesicular body subunit 12B.
   
 0.991
DGUA_6G006879
Blast:Vacuolar protein-sorting-associated protein 36.
    
 0.989
DGUA_6G001916
Blast:Vacuolar protein-sorting-associated protein 25.
    
 0.987
DGUA_6G017713
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
    
 0.979
DGUA_6G013463
Blast:Signal transducing adapter molecule 1.
   
 0.970
DGUA_6G001952
Blast:WD repeat-containing protein 65.
     
 0.933
DGUA_6G013613
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
    
 0.928
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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