Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G004928Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (699 aa)    
Predicted Functional Partners:
DGUA_6G004930
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
   
 
  0.989
DGUA_6G006207
Glucosylceramidase.
   
 
 0.987
DGUA_6G018531
Blast:Ceramide kinase.
    
 0.983
DGUA_6G003179
Blast:Ceramide glucosyltransferase.
     
 0.983
DGUA_6G016092
Blast:Sphingomyelin phosphodiesterase 4.
     
 0.983
DGUA_6G006206
Glucosylceramidase.
   
 
 0.983
DGUA_6G008909
Blast:Ceramide synthase 6.
     
 0.983
DGUA_6G007819
Blast:Sphingomyelin synthase-related 1.
     
 0.982
DGUA_6G004945
Neutral ceramidase.
     
 0.981
DGUA_6G004566
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.981
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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