Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G010345Blast:Rho GTPase-activating protein 190. (2130 aa)    
Predicted Functional Partners:
DGUA_6G001521
Blast:Ras-like GTP-binding protein Rho1.
    
 0.988
DGUA_6G008594
Blast:Ras GTPase-activating protein 1.
   
 0.982
DGUA_6G003714
Tyrosine-protein kinase.
    
 0.764
DGUA_6G008286
Tyrosine-protein kinase.
    
 0.764
DGUA_6G010919
Blast:Probable Ras GTPase-activating protein.
   
 0.732
DGUA_6G016359
Tyrosine-protein kinase.
    
 0.579
DGUA_6G002481
Blast:Rho guanine nucleotide exchange factor 11.
   
 
 0.577
DGUA_6G005611
Blast:Ras-related C3 botulinum toxin substrate 1.
    
 0.576
DGUA_6G007833
Blast:Ras-related protein Rac2.
    
 0.575
DGUA_6G008962
Blast:Cdc42 homolog.
    
 0.575
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (42%) [HD]