Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G011088Calponin-homology (CH) domain-containing protein. (901 aa)    
Predicted Functional Partners:
DGUA_6G008187
Blast:Mitotic spindle assembly checkpoint protein MAD2A.
   
 0.837
DGUA_6G016135
Blast:Cytoskeleton-associated protein 5.
   
 0.834
Lis-1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.
    
 0.795
DGUA_6G000351
Blast:Mitotic spindle assembly checkpoint protein MAD1.
    
 0.792
DGUA_6G002967
Blast:Probable dynactin subunit 2.
    
 0.724
DGUA_6G017650
Blast:Mitotic checkpoint protein BUB3.
   
 0.721
DGUA_6G015276
Blast:CLIP-associating protein.
    
 0.677
DGUA_6G012395
Blast:Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.654
DGUA_6G003709
Blast:Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.654
DGUA_6G014015
Blast:Centromere-associated protein E.
    
 0.631
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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