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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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DGUA_6G012859Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (418 aa)    
Predicted Functional Partners:
DGUA_6G007447
Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
  
0.993
DGUA_6G000089
Blast:Protein N-terminal glutamine amidohydrolase.
      
 0.823
DGUA_6G014202
Blast:Glutaryl-CoA dehydrogenase, mitochondrial.
   
  
 0.823
DGUA_6G007093
Blast:tRNA (Uracil-5-)-methyltransferase homolog A; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
  
  
 0.820
DGUA_6G009560
Blast:YTH domain-containing protein 1.
      
 0.792
DGUA_6G013302
Ubiquitin carboxyl-terminal hydrolase.
      
 0.770
DGUA_6G000957
Queuosine salvage protein; Involved in salvaging queuosine.
     
 0.679
DGUA_6G013078
Blast:tRNA (Cytosine-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.664
DGUA_6G001840
Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily.
  
  
 0.662
DGUA_6G014999
Blast:Transmembrane emp24 domain-containing protein 5.
      
 0.659
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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