Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G011183Blast:39S ribosomal protein L33, mitochondrial. (64 aa)    
Predicted Functional Partners:
DGUA_6G020823
Blast:Signal recognition particle receptor subunit alpha homolog.
  
 0.940
SRP54
Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.
   
 
 0.810
DGUA_6G017286
Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.
    
 
 0.762
DGUA_6G000454
Blast:Ubiquitin-like protein 5.
   
    0.743
DGUA_6G005038
Splicing factor 3B subunit 5; Belongs to the SF3B5 family.
   
    0.703
DGUA_6G015286
Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.
   
 
 0.697
DGUA_6G008207
Blast:Signal recognition particle 19 kDa protein.
   
 
 0.647
DGUA_6G007816
Blast:Translocation protein SEC63 homolog.
   
 
 0.642
DGUA_6G018873
Blast:Translocation protein SEC63 homolog.
   
 
 0.642
DGUA_6G009265
Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
   
 
 0.640
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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