Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G005275Uncharacterized protein. (131 aa)    
Predicted Functional Partners:
DGUA_6G018709
Integrin beta; Belongs to the integrin beta chain family.
    
 0.829
DGUA_6G015363
Blast:Talin-2.
   
 
 0.804
DGUA_6G011436
Blast:Vinculin.
   
 
 0.782
DGUA_6G013940
Integrin beta; Belongs to the integrin beta chain family.
    
 0.679
DGUA_6G007782
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.673
DGUA_6G019100
Blast:Lipoma-preferred partner homolog.
   
 0.658
DGUA_6G016796
Non-specific serine/threonine protein kinase.
    
 0.594
DGUA_6G003806
Blast:Integrin alpha-PS3; Belongs to the integrin alpha chain family.
   
 0.577
DGUA_6G010319
Blast:Integrin alpha-PS1; Belongs to the integrin alpha chain family.
   
 0.577
DGUA_6G019562
Blast:Integrin alpha-PS2; Belongs to the integrin alpha chain family.
   
 0.577
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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