Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G000694Malate dehydrogenase. (350 aa)    
Predicted Functional Partners:
DGUA_6G012156
Aspartate aminotransferase.
   
 0.998
DGUA_6G010234
Citrate synthase; Belongs to the citrate synthase family.
  
 0.994
DGUA_6G017061
Citrate synthase; Belongs to the citrate synthase family.
  
 0.994
DGUA_6G010173
Blast:Fumarate hydratase, mitochondrial.
  
 0.990
DGUA_6G006619
Blast:Probable fumarate hydratase, mitochondrial.
  
 0.990
DGUA_6G010172
Blast:Fumarate hydratase, mitochondrial.
  
 0.990
DGUA_6G013280
Malate dehydrogenase.
   
 
 0.989
DGUA_6G002712
Blast:Probable aspartate aminotransferase, cytoplasmic.
   
 0.988
DGUA_6G006668
Blast:Aspartate aminotransferase, cytoplasmic.
   
 0.988
DGUA_6G005476
Malic enzyme.
  
 0.987
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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