Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G010752Blast:Ankyrin repeat and LEM domain-containing protein 2. (1175 aa)    
Predicted Functional Partners:
DGUA_6G003830
Blast:Serine/threonine-protein kinase VRK1.
   
 0.948
DGUA_6G006086
Blast:Nucleosomal histone kinase 1.
   
 0.947
DGUA_6G004839
Blast:Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit.
    
  0.940
DGUA_6G011962
Serine/threonine-protein phosphatase.
    
 0.936
DGUA_6G012725
Blast:Barrier-to-autointegration factor.
    
 0.925
DGUA_6G015992
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
   
 0.735
DGUA_6G012025
Blast:Protein lethal(2) giant larvae.
    
 
 0.692
DGUA_6G009715
Blast:Charged multivesicular body protein 7.
      
 0.677
DGUA_6G012317
Blast:Enhancer of mRNA-decapping protein 4 homolog.
    
 
 0.628
DGUA_6G006951
Blast:Nucleolar and coiled-body phosphoprotein 1.
    
   0.626
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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