Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G000755Blast:2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (568 aa)    
Predicted Functional Partners:
DGUA_6G011070
Blast:Peroxisomal targeting signal 1 receptor.
 
  
 0.910
DGUA_6G011367
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.894
DGUA_6G020098
Serine--pyruvate aminotransferase.
  
 
 0.876
DGUA_6G003611
Blast:Peroxisomal (S)-2-hydroxy-acid oxidase GLO5.
  
 
 0.868
DGUA_6G002810
Blast:Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial.
    
 0.867
DGUA_6G016374
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.859
DGUA_6G003686
Blast:Mitochondrial intermediate peptidase.
  
 0.842
DGUA_6G005626
Blast:Hydroxysteroid dehydrogenase-like protein 2.
  
 0.842
DGUA_6G013191
Blast:Hydroxymethylglutaryl-CoA lyase, mitochondrial.
  
 
 0.816
DGUA_6G006330
Blast:Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase MESH1.
    
 0.796
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.