Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G010813Blast:DNA repair protein complementing XP-A cells homolog. (295 aa)    
Predicted Functional Partners:
DGUA_6G002004
Blast:DNA excision repair protein ERCC-1.
    
 0.998
DGUA_6G019404
Blast:DNA repair endonuclease XPF.
    
 0.997
DGUA_6G007261
Blast:DNA excision repair protein haywire.
    
 0.994
DGUA_6G003797
Blast:DNA repair protein complementing XP-C cells homolog.
    
 0.992
DGUA_6G019262
Blast:UV excision repair protein RAD23 homolog B.
    
 0.990
DGUA_6G002037
Blast:TFIIH basal transcription factor complex helicase XPD subunit.
    
 0.989
DGUA_6G020553
Blast:Replication protein A 14 kDa subunit.
    
 0.982
DGUA_6G017558
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.980
DGUA_6G004891
Blast:DNA repair protein complementing XP-G cells homolog.
    
 0.980
DGUA_6G001978
Blast:DNA polymerase zeta catalytic subunit.
    
 0.971
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.