Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G005306Blast:Protein cereblon homolog. (620 aa)    
Predicted Functional Partners:
DGUA_6G015709
Blast:DNA damage-binding protein 1.
    
 
 0.987
DGUA_6G003007
Blast:Cullin-4B; Belongs to the cullin family.
    
 
 0.977
DGUA_6G014657
Blast:RING-box protein 1B.
    
 
 0.941
DGUA_6G008403
Blast:RING-box protein 1A.
    
 
 0.941
DGUA_6G004388
Blast:COP9 signalosome complex subunit 2.
   
 
 0.934
DGUA_6G004840
Blast:40S ribosomal protein S13.
    
 
 0.933
DGUA_6G005677
Blast:COP9 signalosome complex subunit 6.
    
   0.932
DGUA_6G018510
Blast:COP9 signalosome complex subunit 5.
    
 
 0.932
DGUA_6G002933
Blast:COP9 signalosome complex subunit 4.
    
 
 0.930
DGUA_6G007482
Blast:COP9 signalosome complex subunit 3.
    
 
 0.928
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.