Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G005404Blast:Cyclin-G2; Belongs to the cyclin family. (561 aa)    
Predicted Functional Partners:
DGUA_6G017211
Blast:Centrosomal and chromosomal factor.
    
 
 0.913
DGUA_6G009576
Blast:G2/mitotic-specific cyclin-A; Belongs to the cyclin family.
   
 0.865
DGUA_6G019244
One cut domain family member.
    
 
 0.833
DGUA_6G006649
Blast:Cyclin-H; Belongs to the cyclin family.
    
 0.819
DGUA_6G009597
Blast:Cyclin-dependent kinase 14.
   
 0.801
DGUA_6G005549
Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.
    
 0.778
DGUA_6G018296
Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.
    
 0.778
DGUA_6G018297
UmuC domain-containing protein.
    
 0.778
DGUA_6G000629
Blast:Protein phosphatase 1 regulatory subunit 15A; Belongs to the cullin family.
    
 0.742
DGUA_6G007313
Blast:NADH-cytochrome b5 reductase 3; Belongs to the cyclin family.
   
 0.733
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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