Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G000899CHK domain-containing protein. (474 aa)    
Predicted Functional Partners:
DGUA_6G016512
Blast:UPF0160 protein MYG1, mitochondrial.
    
   0.946
DGUA_6G002032
HMG box domain-containing protein.
   
   0.926
DGUA_6G013532
Blast:Peptidyl-tRNA hydrolase ICT1, mitochondrial.
   
 0.894
DGUA_6G010887
Blast:Uncharacterized protein CG4951.
    
   0.872
DGUA_6G006406
Blast:Neprilysin-1.
    
 0.763
DGUA_6G013599
Blast:HemK methyltransferase family member 2.
  
 
 0.738
DGUA_6G020158
Blast:HemK methyltransferase family member 1.
  
 
 0.738
DGUA_6G009421
Tyrosine--tRNA ligase.
  
  
 0.715
DGUA_6G017499
Blast:Bifunctional glutamate/proline--tRNA ligase.
  
  
 0.713
DGUA_6G005661
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
    
 
 0.712
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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