Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G005476Malic enzyme. (633 aa)    
Predicted Functional Partners:
DGUA_6G016333
Blast:Malate dehydrogenase, mitochondrial; Belongs to the LDH/MDH superfamily.
  
 0.988
DGUA_6G002711
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.987
DGUA_6G000694
Malate dehydrogenase.
  
 0.987
DGUA_6G013280
Malate dehydrogenase.
  
 
 0.985
DGUA_6G011359
Blast:Alanine aminotransferase 2-like.
  
 0.984
DGUA_6G015475
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.984
DGUA_6G010173
Blast:Fumarate hydratase, mitochondrial.
  
 
 0.983
DGUA_6G006619
Blast:Probable fumarate hydratase, mitochondrial.
  
 
 0.983
DGUA_6G010172
Blast:Fumarate hydratase, mitochondrial.
  
 
 0.983
DGUA_6G006625
Blast:Alsin.
  
 0.983
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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