Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G011738Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (697 aa)    
Predicted Functional Partners:
DGUA_6G008816
Blast:Probable sulfite oxidase, mitochondrial.
      
 0.826
DGUA_6G017570
Blast:Dipeptidyl peptidase 3.
   
  
 0.751
DGUA_6G007604
Blast:Transcription initiation factor TFIID subunit 2.
      
 0.692
DGUA_6G011146
Blast:Probable Xaa-Pro aminopeptidase 3.
  
 
 0.671
DGUA_6G018294
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
  
 0.603
nero
Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. Essential for organismal viability and plays a role in a wide number of important processes such as cell growth and proliferation, and regulates induction of autophagy and protein synthesis. Has a role in eIF-5A- mediated translational control.
  
  
 0.600
DGUA_6G010739
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
      
 0.593
DGUA_6G009910
Blast:Vesicle transport through interaction with t-SNAREs homolog 1A.
      
 0.592
DGUA_6G000186
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.588
DGUA_6G009316
Blast:Phosphoglucomutase.
   
 0.573
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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