Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G011247Blast:E3 ubiquitin-protein ligase HUWE1. (5297 aa)    
Predicted Functional Partners:
DGUA_6G011881
Blast:Ubiquitin-60S ribosomal protein L40.
    
 0.995
DGUA_6G013333
Blast:Ubiquitin-40S ribosomal protein S27a.
    
 0.995
DGUA_6G015151
Blast:Polyubiquitin.
    
 0.986
DGUA_6G008901
Blast:Polyubiquitin.
    
 0.986
DGUA_6G010230
Blast:Transmembrane GTPase Marf; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 0.985
DGUA_6G001986
Peptidylprolyl isomerase.
    
 0.983
DGUA_6G017478
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
    
 0.977
DGUA_6G013057
Blast:Mitochondrial import receptor subunit TOM70.
     
  0.972
DGUA_6G011074
Blast:Mitochondrial import receptor subunit TOM70.
     
  0.972
DGUA_6G011575
Blast:Mitochondrial import receptor subunit TOM70.
     
  0.972
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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