Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DGUA_6G011901Blast:Epidermal growth factor receptor kinase substrate 8. (803 aa)    
Predicted Functional Partners:
DGUA_6G000856
Blast:STE20-like serine/threonine-protein kinase.
    
   0.918
DGUA_6G017719
Blast:Peripheral plasma membrane protein CASK; Belongs to the MAGUK family.
   
 0.899
DGUA_6G015910
Blast:Abl interactor 2.
    
 
 0.844
DGUA_6G014432
Blast:Protein son of sevenless.
    
 
 0.807
DGUA_6G015909
Blast:Twinfilin.
     
 0.709
DGUA_6G006993
Blast:Whirlin.
     
 0.703
DGUA_6G012492
Blast:MAGUK p55 subfamily member 6; Belongs to the MAGUK family.
   
 0.642
DGUA_6G013811
Blast:Neither inactivation nor afterpotential protein C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
     
 0.637
DGUA_6G003161
Receptor protein-tyrosine kinase.
    
 
 0.624
DGUA_6G007994
Blast:SHC-transforming protein 1.
    
 
 0.573
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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