Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G011948Blast:P protein. (851 aa)    
Predicted Functional Partners:
DGUA_6G003575
ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]
    
 0.540
DGUA_6G005174
Blast:Low molecular weight phosphotyrosine protein phosphatase 1.
  
 
 0.537
DGUA_6G017372
Blast:Low molecular weight phosphotyrosine protein phosphatase.
  
 
 0.537
DGUA_6G019069
Uncharacterized protein.
    
 
 0.521
DGUA_6G015333
Blast:Membrane-associated transporter protein.
      
 0.483
DGUA_6G015451
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
     
 0.450
DGUA_6G011949
Uncharacterized protein.
      
 0.438
DGUA_6G002630
KRAP_IP3R_bind domain-containing protein.
      
 0.432
DGUA_6G011950
Blast:Probable 39S ribosomal protein L24, mitochondrial; Belongs to the universal ribosomal protein uL24 family.
      
 0.428
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (42%) [HD]