Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G005736Blast:Protein fork head. (482 aa)    
Predicted Functional Partners:
DGUA_6G008180
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
     
 0.928
DGUA_6G015998
Blast:GATA-binding factor C.
  
 
 0.810
DGUA_6G014475
Blast:T-related protein.
    
 0.748
DGUA_6G016143
Blast:GATA-binding factor A.
  
 
 0.703
DGUA_6G016144
Blast:Transcription factor elt-1.
    
 0.637
DGUA_6G016145
Blast:Box A-binding factor.
    
 0.637
DGUA_6G019848
Blast:Thyroid transcription factor 1.
   
 
 0.633
DGUA_6G005229
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.611
DGUA_6G020227
Blast:Protein groucho.
    
 0.608
DGUA_6G010690
Blast:Homeotic protein ocelliless.
   
 
 0.589
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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