Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G006118G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (715 aa)    
Predicted Functional Partners:
DGUA_6G013769
Blast:Protein smoothened; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.999
DGUA_6G020406
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
     
 0.977
DGUA_6G017118
Blast:Casein kinase I isoform gamma-3; Belongs to the protein kinase superfamily.
     
 0.923
DGUA_6M39
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
     
  0.905
DGUA_6G018679
Blast:Guanine nucleotide-binding protein subunit beta-5.
   
 0.904
DGUA_6G008634
Blast:Guanine nucleotide-binding protein subunit beta-1.
   
 0.904
DGUA_6G009884
Blast:N-alpha-acetyltransferase 60.
     
  0.885
DGUA_6G001820
Blast:G protein alpha q subunit.
    
 0.868
DGUA_6G019025
Blast:PDZ domain-containing protein 8.
     
  0.806
DGUA_6G001724
Blast:ARF GTPase-activating protein GIT1.
   
 
 0.785
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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