Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G006334Blast:CDGSH iron-sulfur domain-containing protein 2 homolog. (132 aa)    
Predicted Functional Partners:
DGUA_6G000448
Blast:CDGSH iron-sulfur domain-containing protein 3, mitochondrial.
   
  
 0.864
DGUA_6G015709
Blast:DNA damage-binding protein 1.
    
 
 0.759
DGUA_6G003007
Blast:Cullin-4B; Belongs to the cullin family.
    
 
 0.657
DGUA_6G011469
Blast:Apoptosis-inducing factor 3.
    
 
 0.655
DGUA_6G004302
Blast:DET1-and DDB1-associated protein 1.
    
 
 0.655
DGUA_6G015274
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 
 0.516
DGUA_6G009896
Blast:B-cell receptor-associated protein 31.
    
   0.469
DGUA_6G011686
Blast:Heat shock factor-binding protein 1.
      
 0.462
DGUA_6G011717
Uncharacterized protein.
   
   0.413
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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