Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G001986Peptidylprolyl isomerase. (393 aa)    
Predicted Functional Partners:
DGUA_6G015274
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.986
DGUA_6G011247
Blast:E3 ubiquitin-protein ligase HUWE1.
    
 0.983
DGUA_6G011622
Blast:Gamma-aminobutyric acid receptor-associated protein.
   
 
 0.983
DGUA_6G015121
Blast:Mitochondrial ubiquitin ligase activator of nfkb 1.
     
 0.981
DGUA_6G011480
Blast:Ubiquitin carboxyl-terminal hydrolase 30; Belongs to the peptidase C19 family.
    
 0.981
DGUA_6G011881
Blast:Ubiquitin-60S ribosomal protein L40.
   
 0.980
DGUA_6G019962
Blast:Gamma-aminobutyric acid receptor-associated protein-like 1.
   
 
 0.980
DGUA_6G017478
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
   
 0.979
DGUA_6G008503
RBR-type E3 ubiquitin transferase.
     
 0.979
DGUA_6G013333
Blast:Ubiquitin-40S ribosomal protein S27a.
   
 0.978
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (50%) [HD]