Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G013093Blast:Menin. (764 aa)    
Predicted Functional Partners:
DGUA_6G014550
Blast:Retinoblastoma-binding protein 5 homolog.
   
 0.932
DGUA_6G013775
Blast:Stress-induced-phosphoprotein 1.
   
 0.915
DGUA_6G006598
Blast:Heat shock 70 kDa protein 4L.
  
 0.878
DGUA_6G015890
Histone-lysine N-methyltransferase trithorax; Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes. Acts as an activator of BX-C. Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo.
    
 0.861
DGUA_6G013860
Blast:DnaJ homolog subfamily A member 2.
   
 0.801
DGUA_6G015656
Blast:DnaJ homolog subfamily A member 1.
   
 0.801
DGUA_6G016281
Blast:Nucleotide exchange factor SIL1.
   
 
 0.799
DGUA_6G018365
Blast:Protein AF-9.
    
 
 0.797
DGUA_6G020300
Blast:BAG family molecular chaperone regulator 2.
   
 
 0.781
DGUA_6G008147
Blast:PAX-interacting protein 1.
    
 
 0.778
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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