Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G013464Blast:Aurora kinase B; Belongs to the protein kinase superfamily. (329 aa)    
Predicted Functional Partners:
DGUA_6G000537
Blast:Inner centromere protein.
   
 0.999
DGUA_6G004429
Blast:Borealin.
   
 0.984
DGUA_6G015985
Blast:Baculoviral IAP repeat-containing protein 5.
   
 0.984
DGUA_6G007466
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.968
DGUA_6G003709
Blast:Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.954
DGUA_6G014588
Blast:Bipolar kinesin KRP-130; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.953
DGUA_6G017650
Blast:Mitotic checkpoint protein BUB3.
   
 0.941
DGUA_6G013109
Blast:Cell division cycle protein 20 homolog.
   
 0.941
DGUA_6G007570
Blast:Separin.
   
 
 0.936
DGUA_6G021251
Histone H3; Belongs to the histone H3 family.
   
 
 0.936
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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