Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G005131Blast:Bromodomain adjacent to zinc finger domain protein 1A. (1507 aa)    
Predicted Functional Partners:
DGUA_6G003839
Blast:Chromatin-remodeling complex ATPase chain Iswi.
   
 0.997
DGUA_6G010129
Blast:Chromatin accessibility complex protein 1.
   
 0.992
DGUA_6G004890
Blast:DNA polymerase epsilon subunit 3.
    
 0.991
DGUA_6G005229
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.910
DGUA_6G010025
Blast:Cat eye syndrome critical region protein 2.
   
0.883
DGUA_6G015431
Blast:Transcription factor RFX3.
    
 
 0.733
DGUA_6G010499
Histone H2B; Belongs to the histone H2B family.
    
 0.711
DGUA_6G020689
Histone H2B; Belongs to the histone H2B family.
    
 0.711
DGUA_6G013729
Histone H2B; Belongs to the histone H2B family.
    
 0.711
DGUA_6G009239
Blast:Nucleosome-remodeling factor subunit NURF301.
   
 
0.701
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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